What Is The Difference Between API And Intermediate?

- Dec 01, 2020-

What is the difference between API and intermediate?


What is an intermediate product?

Our chemical products include vitamins, disperse dyes, couplers, curing agents, etc. So what is an intermediate? What is the difference between it and API?


Intermediates are also called organic intermediates. Coal tar or petroleum products are used as raw materials for intermediate products such as dyes, pesticides, drugs, resins, additives, and plasticizers. Since it was originally used to make dyes, the intermediates are also called dye intermediates. It is formed by the reaction (sulfonation, alkali melting, nitration, reduction, etc.) of cyclic compounds (such as benzene, naphthalene, anthracene, etc.).


Initially, intermediates were produced from coal tar or petroleum products in the process of synthesizing fragrances, dyes, resins, drugs, plasticizers, rubber accelerators and other chemical products. Now they mentioned various intermediates produced in organic synthesis.


Intermediate products refer to semi-finished products, which are intermediate products of certain products. For example, to produce products, you can produce from intermediate products to save costs. Pharmaceutical production requires a large number of special chemicals, most of which were originally produced by the pharmaceutical industry. However, as the division of labor in society continues to deepen and production technology advances, the pharmaceutical industry will transfer the production of some pharmaceutical intermediates to chemical companies. Pharmaceutical intermediates are fine chemical products. The production of pharmaceutical intermediates has become a major industry in the international chemical industry.



What is the difference between API and intermediate?

Intermediate is a kind of material produced in the production process of API and can only be transformed into API through further molecular changes or refinement. The intermediates may or may not be separated.


API is the active pharmaceutical ingredient. A substance or any mixture of substances used in the manufacture of medicines. When used in medicine, it is also the active ingredient in medicine. Such substances have pharmacological or other direct effects in the diagnosis, treatment, alleviation, treatment or prevention of diseases, or may affect the function and structure of the body.


It can be seen from the definition that the intermediate is the key product of the previous API preparation process, which is different from the structure of the API. In addition, the Pharmacopoeia can be used to detect APIs, but no intermediates.